Email : m_hoque@aliah.ac.in

Address : Faculty Room Department of Biological Sciences 8th Floor, New Town Campus

Joined : 11/09/2017

 Applied Bio-Chemistry Lab

Lab Webpage: https://sites.google.com/view/mhlab

Education

2012-2016                              

Ph.D. (Biotechnology), Aligarh Muslim University, India.

Thesis title: Effect of oleic acid complex of α-lactalbumin on mammalian erythrocyte membrane. Supervisor: Prof. M. Saleemuddin.

2011-2012                              

M.Phil. (Biotechnology), Aligarh Muslim University, India.

Thesis title: Studies on oleic acid complexes of some proteins with antitumor properties (Studies on BAMLET). Supervisor: Prof. M. Saleemuddin.

2008-2010                              

M.Sc. (Biotechnology), North Eastern Hill University, India

Dissertation title: Analysis of phenetic relationship among Neolissochilus hexagonolepis and five other cyprinids of Meghalaya and Assam using ISSR markers. Supervisor: Dr. M.A. Laskar.

2005-2008                              

B.Sc. (Zoology), Gauhati University, India.

Project title: “Monitoring the population trend of Greater Adjutant Stork (Leptoptilos dubius) from summer to winter seasons in Guwahati Municipal Area”. Funded by Rufford Small Grants Foundation, London through Aaranyak’s Student grant (2007-08). PI: Dr. Mridul Borthakur.

Industrial Experience

January 2011-April 2011

R & D Trainee at Bhat Biotech India Private Ltd. Bangalore under Biotech Industrial Training Programme of Biotech Consortium India Limited.

Field of Specialization

Protein Chemistry & Engineering, Membrane Biology, Cancer Biology.

Courses Taught/Teaching

Biomolecules, Biophysics, Animal Diversity, Animal Behavior

Experience

July 2016 to September 2017       

Postdoctoral Research Associate (Department of Biotechnology, Govt. of India), Assam University, Silchar, India.

Conference Papers Published

1. Mehboob Hoque, Jyoti Gupta, M. Saleemddin (2013).“Ion channel mediated hemolysis of anucleated and nucleated erythrocytes by Bovine α-Lactalbumin Made Lethal to Tumor cells (BAMLET)” at the National Symposium on “Modern Trends in Human Diseases”organized by Indian Academy of Biomedical Sciences (IABS) and Department of Biochemistry, JN Medical College, AMU, Aligarh, India.

2. Munazza T. Fatima, Ejaj Ahmad, Mehboob Hoque, M. Owais, M. Saleemuddin (2013). “Plasma microparticles as potential drug/vaccine delivery candidates” at the National conference on “Nanoscience and Nanotechnology” conducted by Department of Applied Physics, Z. H. College of Engineering, AMU, Aligarh, India.

3. Mehboob Hoque, Munazza T. Fatima, Jyoti Gupta, M. Saleemuddin (2013). “Oleic Acid Plays the Seminal Role in the BAMLET-induced Erythrocyte Hemolysis” at the foundation day symposium on “Current Trends in Biotechnology”at Interdisciplinary Biotechnology Unit, AMU, Aligarh, India.

4. Mehboob Hoque, Jyoti Gupta, Pawan Gupta, M. Saleemuddin (2015). “HAMLET-like complexes with enhanced cytotoxicity” at Global Cancer Summit, 2015 at Indian Institute of Science, Bangalore, India.

5. Mehboob Hoque, Jyoti Gupta, M. Saleemuddin (2016). “BAMLET is depleted of oleic acid on interaction with cells” at the National Symposium on “Biomedical Sciences in 21^st Century and Beyond”organized by Indian Academy of Biomedical Sciences (IABS) and Department of Biochemistry, Medanta, the Medicity, Gurgaon, India.

Journal Papers Published

1. MunazzaTamkeen Fatima, Ejaj Ahmad, Mehboob Hoque (2017). Effective antigen delivery via dual entrapment in erythrocytes and autologous plasma beads. Journal of Drug Targeting, Jul 3:1-31. doi: 10.1080/1061186X.2017.1350859.IF:3.068

2. Mehboob Hoque, Jyoti Gupta, M. Saleemuddin, (2017). Augmenting the Cytotoxicity of Oleic Acid-Protein Complexes: Potential of Target-Specific Antibodies.Biochimie, 137:139-146. doi: 10.1016/j.biochi.2017.03.013. IF: 3.112

3. Jyoti Gupta, Mehboob Hoque, Masihuz Zaman, Rizwan Hasan Khan, M. Saleemuddin (2016). A detergent-based procedure for the preparation of IgG-like bispecific antibodies in high yield. Scientific Reports, 6:39198,doi: 10.1038/srep39198. IF: 4.259, Citations:  2

4. Mehboob Hoque, Jyoti Gupta, Gulam Rabbani, Rizwan Hasan Khan, M. Saleemuddin (2016). Behaviour of Oleic acid-Depleted Bovine Alpha-Lactalbumin Made LEthal to Tumor cells (BAMLET). MolecularBioSystems, 12(6):1871-80. doi: 10.1039/c5mb00905g. IF: 2.781, Citations:  3

5. Ejaj Ahmad, Munazza T Fatima, Mehboob Hoque, Mohammad Owais, Mohammed Saleemuddin (2015) Fibrin matrices: The Versatile Therapeutic Delivery Systems. International Journal of Biological Macromolecules, 81: 121–136. doi: 10.1016/j.ijbiomac.2015.07.054. IF: 3.671, Citations:  6

6. Mehboob Hoque, Ravikanth Nanduri, Jyoti Gupta, Sahil Mahajan, Pawan Gupta, M. Saleemuddin (2015) Oleic acid complex of bovine α-lactalbumin induces eryptosis in human and other erythrocytes by a Ca²⁺-independent mechanism. BiochimicaEtBiophysicaActa-General Subjects, 1850 (9): 1729-1739. doi: 10.1016/j.bbagen.2015.04.009. IF: 4.702, Citations:  11

7. Mehboob Hoque, Sandeep Dave, Pawan Gupta, Mohammed Saleemuddin (2013) Oleic Acid May Be the Key Contributor in the BAMLET-induced Erythrocyte Hemolysis and Tumoricidal Action. PloS ONE 8(9): e68390. doi: 10.1371/journal.pone.0068390. IF: 2.806, Citations:  29.

8. Hoque M, Safdar Ali, Hoda M (2018) Current status of G-protein coupled receptors as potential targets against type 2 diabetes mellitus. International Journal of Biological Macromolecules, 118:2237-2244 https://doi.org/10.1016/j.ijbiomac.2018.07.091

Membership Of Learned Societies

1. Member, Indian Academy of Biomedical Sciences (IABS).
2. Life Member, Indian Science Congress
3. Life Member, Indian Biophysical Society

Other Notable Activities

Editorial Board Member of E Chronicon Proteomics and Bioinformatics